Completion of the Human Genome Project
By the time the Human Genome Project was completed in 2004, the gene had long been a cultural icon [...]
The International Human Genome Sequencing Consortium, led in the United States by the National Human Genome Research Institute (NHGRI) and the Department of Energy (DOE), published, in 20 October 2004, its scientific description of the finished human genome sequence, reducing the estimated number of human protein-coding genes from 35,000 to only 20,000-25,000, a surprisingly low number for our species.
The paper appears in the Oct. 21 issue of the journal Nature. In the paper, researchers describe the final product of the Human Genome Project, which was the 13-year effort to read the information encoded in the human chromosomes that reached its culmination in 2003. The Nature publication provides rigorous scientific evidence that the genome sequence produced by the Human Genome Project has both the high coverage and accuracy needed to perform sensitive analyses, such as focusing on the number of genes, the segmental duplications involved in disease and the "birth" and "death" of genes over the course of evolution.
National Human Genome Research Institute
Download the complete NHGRI release hereDownload the complete article published in Nature hereLearn more in a complete timeline of the Human Genome Project:
About NHGRI: A Brief History and Timeline
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