Neuroscience Research Agenda to Guide Development of a Pathophysiologically Based Classification System, by Charney et al.

In 2002, in a contribution to the preparation of the fifth edition of the DSM, the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders (released in 2013), a group of prominent biological psychiatrists remarked that psychiatry had “thus far failed to identify a single neurobiological phenotypic marker or gene that is useful in making a diagnosis of a major psychiatric disorder or for predicting response to psychopharmacologic treatment” (Charney et al. 2002, 33). Over a decade later the situation has not changed.

Vidal, Fernando and Ortega, Francisco. Being Brains: Making the Cerebral Subject (Forms of Living)....